Retinol is a form of vitamin A that helps prevent clogged pores and increases skin cell turnover and collagen production. Its effects and its side effects are different things. Temporary dryness, flaking or peeling can settle while you continue using the treatment.1

Does retinol stop working over time?

Less irritation does not tell you that retinol has stopped working. Judge progress by changes in the concern you are treating, such as texture or fine lines, rather than how eventful application feels, because skincare does not need to provide nightly entertainment. Whether a particular product's benefits plateau over years is less clear; skin adjustment alone cannot answer that.1

Should I increase retinol strength if it stops working?

Not simply because it no longer irritates. Start with the least intense formula and build up use slowly. Prescription strength retinoids are not necessary for most people, although they can work faster for some. If regular use has not helped, a dermatologist can assess whether a prescription product makes sense.123

If you already use a retinol serum, you probably do not need retinol in your moisturizer too.3

How long does retinol take to work?

Retinol starts acting in your cells immediately, but visible improvement takes several weeks. With regular use of an over the counter product, expect improvements around three months. Fine lines and dark spots can take several months. Acne can initially look worse, and pimples can continue during the first couple of months.13

How to help your skin adjust

  1. 1Test a little on a small area first. Check for redness or itching over a couple of days before starting.
  2. 2At night, wash with a gentle cleanser and pat dry. Do not scrub.
  3. 3Follow the package directions. General facial guidance is a thin, pea sized amount, avoiding the eyes, mouth and nose.
  4. 4Start every other night, or less frequently if needed, and increase gradually as tolerated.
  5. 5Finish with moisturizer. A thin layer before retinol is another option if application is irritating.
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Use sunscreen of at least SPF 30 during the day, along with shade and protective clothing. If your skin becomes too dry or irritated, pause for a few days rather than pushing through.234

Do not use retinoids during pregnancy. Skin allergies, marked dryness, redness or inflammation are reasons to discuss alternatives with a dermatologist. With darker skin, irritation can trigger dark marks, making a slow start and moisturizer especially useful.2

Where this answer comes from

  1. 1Retinol: Cream, Serum, What It Is, Benefits, How To Usemy.clevelandclinic.org
  2. 2Retinoid or retinol?aad.org
  3. 3Anti-Aging Skin Care: Ingredients and Routinehealth.clevelandclinic.org
  4. 4Keratosis pilaris: Self-careaad.org