Azelaic acid cream treats acne, while prescription gel and foam treat the bumps and swelling of rosacea, a condition that causes facial redness, flushing and pimples. For a cosmetic azelaic acid product, follow its own label rather than borrowing the prescription schedule.1

Can you apply it more often or skip a dose?

Use prescription azelaic acid at around the same times each day. Do not use more product or apply it more often than prescribed. If you miss an application, apply it when you remember unless the next dose is nearly due. In that case, skip the missed dose and return to your usual schedule. Do not double the next dose.1

How often should you use azelaic acid for rosacea?

Prescription azelaic acid gel or foam is generally used twice daily for rosacea breakouts. Finacea 15% gel specifically treats raised inflamed bumps and pus filled spots in mild to moderate rosacea. If you have persistent redness without bumps, discuss treatment for that symptom rather than assuming the same gel will address it.23

A gentle cleanser, moisturizer and sunscreen make up the skincare part of a rosacea treatment plan, not a bathroom shelf expansion programme.2

How do you apply azelaic acid?

  1. 1Wash the affected skin with a very mild soap or soapless cleansing lotion, then pat dry with a soft towel.
  2. 2For prescription gel or cream, apply a thin layer to the affected skin and gently massage it in. For prescription foam, shake the container first and apply a thin layer across the face, including the cheeks, chin, forehead and nose.
  3. 3Leave the treated skin uncovered. Do not cover it with bandages, dressings or wrappings.
  4. 4Let the medication dry before applying makeup.
  5. 5Wash your hands after application.
14

With prescription 15% gel, avoid alcohol based cleansers, astringents, abrasive products and peeling agents. Tell your prescriber which other medicines and skincare treatments you use before combining them. Azelaic acid is an accepted acne treatment option, but that does not mean every combination belongs in your routine.145

For acne, choose non comedogenic skincare and makeup, meaning products less likely to block pores, which is a more useful qualification than looking coordinated on a shelf.6

How long should you give it?

For rosacea breakouts, topical treatments can show slight improvement in 3 or 4 weeks; a noticeable difference usually takes 2 to 3 months. Arrange a review if prescription 15% gel has not helped after 12 weeks. Acne treatments can also take up to 3 months to work. See a GP sooner for deep, painful spots, scarring or acne affecting your mental health.2467

When should you stop or get advice?

Burning, stinging and itching can occur, particularly during the first few weeks of prescription gel use. Stop and contact your prescriber if severe irritation develops and persists. Report skin lightening, especially on darker skin, or worsening asthma. Keep azelaic acid away from your eyes and mouth; rinse accidental eye exposure with plenty of water and seek advice if irritation persists.3

Stop using azelaic acid and get immediate medical help for facial, lip or tongue swelling, difficulty breathing or swallowing, hives or a rash.1

If you are pregnant, planning pregnancy or breastfeeding, discuss use with your prescriber. Topical azelaic acid is minimally absorbed into the body, but pregnancy decisions should follow your specific prescription. Prescription foam is flammable: avoid flames and smoking during application and briefly afterwards.14

Where this answer comes from

  1. 1Azelaic Acid Topical : MedlinePlus Drug Informationmedlineplus.gov
  2. 2Rosacea: Diagnosis and treatmentaad.org
  3. 3These highlights do not include all the information needed to use FINACEA® Gel safely and effectively. See full prescribing information for FINACEA Gel. FINACEAdailymed.nlm.nih.gov
  4. 4These highlights do not include all the information needed to use AZELAIC ACID GEL safely and effectively. See full prescribing information for AZELAIC ACID GELdailymed.nlm.nih.gov
  5. 5Acne clinical guidelineaad.org
  6. 6NHS 111 Wales - Health A-Z : Acne111.wales.nhs.uk
  7. 7Acnenhs.uk