How does glycolic acid help?
Closed comedones are whiteheads: small, usually uninflamed bumps with a blocked follicle and skin covering the opening. They can look skin coloured rather than white. The blockage contains skin cells and sebum, the skin's natural oil. Unlike a blackhead, the contents are not exposed at the surface.34
Glycolic acid is an alpha hydroxy acid. It reduces how tightly dead skin cells stick together and helps correct the cell buildup inside the follicle opening. That makes it useful for reducing plugs, rather than simply making the surface feel smoother. Professional chemical peels can also be used alongside other acne treatments.1
Do you need a stronger glycolic acid?
Not necessarily. In a trial of 80 adults with mild to moderate acne, a daily 5% glycolic acid complex and four professional 20% glycolic peels both reduced acne lesions. The reduction in comedones was similar between the groups at the 70 day assessment. The 5% formula also contained other ingredients, including allantoin and trehalose. Those results apply to that formula and treatment schedule, not every bottle marked 5%.5
How should you use it?
- 1Wash gently with a mild cleanser. Do not scrub the bumps.
- 2For a topical comedonal acne treatment, apply a thin layer across the affected area rather than treating only individual bumps. Follow the particular product's application directions; the daily schedule for the studied 5% complex is not a schedule for every glycolic product.
- 3Moisturize as part of your morning and evening skin care.
- 4Wear sunscreen daily. Leave concentrated glycolic peels to a licensed professional rather than copying a clinic treatment at home.
A treatment plan can use more than one acne medicine to address different causes, but the combination should have a purpose. Choose treatments for their jobs, rather than staffing the bathroom shelf with several products doing the same shift.2
How long does it take?
Expect gradual improvement, not immediate removal of every plug. Acne treatment generally takes at least six to eight weeks before fewer breakouts appear. Comedonal acne can take eight to 12 weeks to show a noticeable difference and many months to clear. Continued treatment is often needed because comedones can return.246
Does salicylic acid help closed comedones?
Yes. Salicylic acid opens clogged pores and treats whiteheads. It dissolves into oil, helping it penetrate the follicle and loosen plugs. It comes in several forms, including cleansers and moisturizers. A separate exfoliating bottle is not compulsory, even if the bathroom shelf has already reserved its seat.12
For persistent whiteheads, an acne retinoid is another direct option: dermatologists recommend retinoids to unclog pores. Adapalene is available without a prescription in the US. If you already have a prescription acne routine, discuss where glycolic acid fits rather than changing your medicines yourself.27
Who should be careful?
Glycolic treatments can cause adverse effects, and chemical peels can leave dark marks after inflammation, particularly in darker skin. Sensitive skin, pregnancy, breastfeeding and recent isotretinoin use need individual advice before choosing a glycolic treatment; these groups were excluded from the 5% versus 20% trial. If treatment causes side effects, contact your clinician. If bumps remain despite consistent treatment, a dermatologist can assess them and discuss prescription treatment or professional extraction. Do not squeeze or puncture them yourself: home extraction can cause scarring, infection and further follicle damage.1457
Where this answer comes from
- 1Chemical Peels for Acne and Acne Scars in Asians: Evidence Based Reviewpmc.ncbi.nlm.nih.gov
- 2Acne: Diagnosis and treatmentaad.org
- 3Comedodermnetnz.org
- 4Comedonal Acne: Causes & Treatmentmy.clevelandclinic.org
- 5Effect of 5% glycolic acid complex and 20% glycolic acid on mild-to-moderate facial acne vulgarispmc.ncbi.nlm.nih.gov
- 6Comedonal acnedermnetnz.org
- 7How to treat different types of acneaad.org