The exact Regenerating Serum discussed here is Olay Canada's 50 ml fragrance free version; US MAX Wrinkle and Micro Sculpting serums and the UK Niacinamide24 serum are different products. The Regenerist name covers several serums, which makes the family name less useful than the small print.1234

Is Olay Regenerist good?

It is a reasonable option if you want lightweight hydration and help with the appearance of fine lines. Niacinamide, also called nicotinamide, is vitamin B3. It can strengthen the skin barrier, the outer layer that helps keep water in, and improve hydration. Clinical studies of topical niacinamide have also found improvements in fine lines, uneven pigmentation, texture and elasticity. Those ingredient benefits make niacinamide useful in skincare, but the percentage and complete formula matter when choosing a particular serum.5

What results should you expect?

Olay describes immediate softening from hydration and visible improvements in wrinkles and firmness after two weeks. Its Canadian Regenerating Serum page also gives a four week wrinkle claim, so treat two to four weeks as the brand's stated window rather than a fixed deadline.1

For niacinamide generally, studies have assessed wrinkle improvements over eight to twelve weeks. One twelve week study used 5% niacinamide; another eight week study used 4%. These are useful expectations for the ingredient, not a reason to assume the Olay serum contains either concentration. Think of hydration and longer term changes in skin appearance as separate results.5

How do you use Olay Regenerist Regenerating Serum?

  1. 1Wash your face thoroughly.
  2. 2Gently smooth the serum evenly over your face and neck until absorbed.
  3. 3Once the serum has absorbed, apply moisturizer.
  4. 4Repeat morning and night. You can apply makeup over the serum.
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Include sunscreen in your daytime routine. Niacinamide does not prevent sunburn, and the US MAX serum directions also tell you to use SPF during the day. Do not confuse the serum with Olay Regenerist Regenerating Moisturizer Broad Spectrum SPF 15, a separate sunscreen lotion with its own directions.256

What are the ingredients in Olay Regenerist Serum?

The Canadian Regenerating Serum contains water, dimethicone, glycerin, niacinamide, panthenol, palmitoyl pentapeptide 4, tocopheryl acetate, allantoin and green tea leaf extract, alongside other formula ingredients. Olay identifies panthenol as pro vitamin B5, palmitoyl pentapeptide 4 as its amino peptide, and tocopheryl acetate as vitamin E. Niacinamide and peptide percentages are not disclosed, so there is no numerical strength to compare with a serum that states its concentration.1

Which Regenerist serum are you buying?

Product and marketFormula and feelDirections and listed price
Regenerating Serum Fragrance Free, Canada, 50 mlNiacinamide and palmitoyl pentapeptide 4; lightweight and fast absorbing.Morning and night before moisturizer. No price stated.
Niacinamide MAX Wrinkle Reducing Serum, USNiacinamide, palmitoyl pentapeptide 4 and palmitoyl dipeptide 7; fragrance free, with a nonsticky, nongreasy feel.Day and night before moisturizer; daytime SPF. Listed at US$46.65.
Micro Sculpting Serum Fragrance Free, USNiacinamide, panthenol and palmitoyl pentapeptide 4; lightweight, creamy and nongreasy.Smooth over cleansed face and neck morning and night. Listed at US$36.65.
Niacinamide24 + Vitamin E Age Defy Serum, UK, 40 mlNiacinamide and vitamin E; fragrance free, lightweight and nongreasy.Routine places serum after cleansing and before moisturizer. No price stated.
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The Canadian MAX Wrinkle Serum is a 40 ml option containing two named peptides, niacinamide, panthenol and vitamin E. Olay's claim of twice the peptides compares MAX with Olay Wrinkle Correction Serum, not the original Regenerating Serum. The Canadian MAX formula is made without fragrance, parabens, phthalates, mineral oil or synthetic dyes. Its directions specify a generous, even layer before moisturizer, morning and night.7

Choose the Canadian Regenerating Serum if you want the exact product named here. Consider US MAX if you prefer its two peptide formula and Olay's stated suitability for oily, normal and dry skin. Consider US Micro Sculpting if you want the creamy texture Olay describes and the lower listed price of those two US options. The UK Niacinamide24 serum is another lightweight option focused on hydration, niacinamide and vitamin E, rather than an interchangeable bottle of the Canadian formula.234

For the UK serum, Olay claims immediate hydration lasting 24 hours and reduced visible fine lines and wrinkles after 14 days. Its claim of 99% niacinamide purity describes the ingredient's purity, not a serum containing 99% niacinamide. Olay also describes testing on more than 100 women with different skin tones.4

What if your skin is sensitive?

Topical niacinamide is generally well tolerated and can often be used by people who cannot tolerate topical retinoids or fruit acids. That makes the ingredient worth considering if stronger treatments are uncomfortable. Studies of niacinamide moisturizers have also found improved barrier function and reduced reactions to irritants. Choose based on the complete product, rather than treating an ingredient's tolerability as a prediction of how your skin will respond to the serum.5

Has Olay Regenerist Serum been discontinued?

A worldwide discontinuation of Regenerating Serum is not confirmed. Olay Canada lists the 50 ml Regenerating Serum Fragrance Free, while Olay's US store lists Micro Sculpting Serum Fragrance Free and Niacinamide MAX Wrinkle Reducing Serum. The US store gives the two serums separate listings, because apparently Regenerist needed its own filing system. If you are trying to replace an old bottle, match the full name and country rather than assuming MAX or Micro Sculpting is the same formula under a new name.123

Where this answer comes from

  1. 1Regenerist Regenerating Serum Fragrance-Freeolay.ca
  2. 2Regenerist MAX Wrinkle Serum Peptidesolay.com
  3. 3Olay Regenerist Micro-Sculpting Serum Fragrance Free – Page 4olay.com
  4. 4Olay Niacinamide24 + Vitamin E Age Defy Serumolay.co.uk
  5. 5Nicotinamidedermnetnz.org
  6. 6Olay ® Regenerist ® Regenerating Moisturizer Broad Spectrum SPF 15dailymed.nlm.nih.gov
  7. 7Olay Regenerist MAX Wrinkle Serum with Peptides, 40 mLolay.ca