What does adapalene do for acne?

Who is adapalene for?

Adapalene is used to treat acne in adults and children aged 12 years and older. It is especially relevant when blackheads and whiteheads are a concern because retinoids help unclog pores.12

Topical acne treatments, including adapalene, are commonly used for mild acne. They are applied to the affected area rather than dabbed only on the pimples you can see. For moderate acne, topical treatment may be combined with oral medicine. Severe acne, deep nodules or cysts need medical care because these lesions can leave scars.26

How to use adapalene gel

1. 1Wash the affected skin gently with a mild soap or soapless cleanser, then pat it dry with a soft towel. Do not scrub or use a harsh, abrasive cleanser.
2. 2Use your fingers to spread a thin film over the entire acne affected area, not only over one pimple or spot.
3. 3Apply adapalene once a day at bedtime, following the package or prescription directions. Using more or applying it more often will not speed results and can irritate your skin.
4. 4If you miss a dose, apply it when you remember unless it is nearly time for the next one. Skip it in that case and do not double the next dose.

Do not apply adapalene to sunburned, broken or eczematous skin until it has healed. Keep it away from your eyes, nose, mouth and vagina; if it gets in your eyes, redness, irritation or swelling can occur.1

Adapalene can make skin more sensitive to sunlight and ultraviolet light. Avoid unnecessary or prolonged sun exposure, including tanning beds and sunlamps, and use sunscreen and protective clothing when outdoors.1

Harsh or drying skin products and products containing alcohol can add irritation when used with adapalene. Tell your clinician about the skin care products and medicines you use so they can help you choose a routine that is less irritating. For blackheads and whiteheads, a benzoyl peroxide wash can be used alongside a retinoid to help reduce excess acne bacteria.12

What results should you expect?

Acne can look worse during the first few weeks, and adapalene can bring previously unseen pimples to the surface. The full benefit can take 8 to 12 weeks or longer, so a slow start does not mean the treatment has failed. Applying extra adapalene will not make it work faster.1

Adapalene side effects

Redness, scaling, dryness, burning or stinging, and pain where you apply adapalene can occur. Dryness and irritation are common during the first 2 to 4 weeks of treatment. A slight warmth or brief sting can happen after application and should pass on its own.1

If burning, stinging or irritation is severe or does not settle, contact your clinician. They may suggest a moisturizer or tell you to apply adapalene less often. Stop using it and seek medical advice if severe irritation develops.16

Hives, itching, trouble breathing, or swelling of the eyes, face, lips, tongue or throat can signal a serious reaction. Get medical help immediately if these symptoms occur.1

If you are pregnant, planning a pregnancy or breastfeeding, speak with your clinician before starting adapalene. If a clinician advises using it while breastfeeding, use the smallest amount and do not apply it directly to the nipple or areola.17

When should you get medical advice?

See a doctor or dermatologist if your acne is severe, includes deep nodules or cysts, is getting worse, leaves scars, or remains a problem after several months of treatment. Get help sooner if acne is causing emotional distress.46